H <sub>2</sub> O <sub>2</sub> ‐Triggered Self Immolative Prodrug Nanoassemblies as Self‐Deliverable Nanomedicines for Targeted On‐Demand Therapy of Thrombotic Disorders (Adv. Therap. 6/2021)
نویسندگان
چکیده
A thrombus is composed of fibrin, activated platelets and leukocytes the formation an occlusive a critical pathophysiological feature numerous cardiovascular diseases. Here, self-immolative prodrug (Fu-sBR) nanoassemblies are developed for targeted on-demand therapy thrombotic disorders. Fu-sBR target P-selectin on exert antioxidant, anti-inflammatory antiplatelet activities to suppress formation. This reported by Dongwon Lee co-workers in article number 2000273.
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ژورنال
عنوان ژورنال: Advanced therapeutics
سال: 2021
ISSN: ['2366-3987']
DOI: https://doi.org/10.1002/adtp.202170013